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add to favorites	Supply high quality Nootropic Hydrafinil Powder (9-Fluorenol) CAS 1689-64-1	Cars - Economy cars
Supply high quality Nootropic Hydrafinil Powder (9-Fluorenol) CAS 1689-64-1 Hydrafinil, also known by its formal name 9-Fluorenol, is a eugeroic drug. state that it is more effective at keeping the target of the drug awake. In fact, an animal study conducted by Cephalon reported a 39% increase in effectiveness at keeping the mice awake over a 4 hour period. In addition, hydrafinil powder is a weaker dopamine reuptake inhibitor . Hydrafinil;Fluorenol is an alcohol derivative of fluorene. In the most significant isomer, fluoren-9-ol or 9-hydroxyfluorene, the hydroxy group is located on the bridging carbon between the two benzene rings. Hydroxyfluorene can be converted to fluorenone by oxidation. Quick Details CAS No.: 1689-64-1 Other Names: 9-Fluorenol MF: C13H10O EINECS No.: 216-879-0 Place of Origin: Hubei, China Type: Central Nervous System Agents, Vitamins, Amino Acids and Coenzymes Grade Standard: Food Grade, Medicine Grade Usage: Animal Pharmaceuticals Brand Name: None Model Number: Hydrafinil 99% Purity: Hydrafinil 99% Product Name: Hydrafinil (9-Fluorenol) Appearance: White to off-white crystalline powder or lumps Shelf Life: 2 Years Molecular Formula:: C13H10O CAS Number:: 1689-64-1 Eniecs:: 216-879-0 Grade: food grade MOQ: 1KG sample: free sample Package: 25KG/drum
add to favorites	HYDRAFINIL (9-FLUORENOL) 139% EFFECTIVENESS OVER MODAFINIL	Cars - Economy cars
HYDRAFINIL (9-FLUORENOL) 139% EFFECTIVENESS OVER MODAFINIL 9-Fluorenol powder (Fluorenol) a modafinil analog - research chemical originally made by Cephalon Pharma. It is a powerful eugeroic (wakefulness-promoting agent) under consideration to be the next step up from Provigil (Modafinil) Clinical study showed that fluorenol exhibited a 39% increase in wakefulness over modafinil. Hydrafinil, also know under the name Fluorenol or 9-Fluorenol is a synthetic eugeroic or wakefulness enhancing substance. It has a 39% higher effectiveness in its effects than modafinil and is handled as a theoretical successor of the same. It is a weak dopamine reuptake inhibitor, being notably 59% weaker in comparison than modafinil albeit being a stronger eugeroic, resulting in a lesser liability for addiction. Fluorenol has shown enhancements in short-term visual memory, attention and information processing as well as a decrease in impulsivity and an increase in logical thinking.
add to favorites	Are Nootropics Legit Or Just Another Health Fad?	Cars - Economy cars
Are Nootropics Legit Or Just Another Health Fad? People take supplements for all kinds of reasons: for a healthy pregnancy, for thicker hair, for fewer headaches, for stronger bones, and so on. But some health-conscious people are drawn to a type of supplement called nootropics, because they promise to improve your mental performance and make you smarter. Moon Juice sells a nootropic Reishi mushroom powder that it says is a, "powerful brain tonic, long used to energize and enhance mood, and support concentration." Sounds promising, but what even does that mean?Glycine Propionyl-L-Carnitine powder "Nootropic" essentially means something that enhances your cognition, says Philip Muskin, MD, professor of psychiatry at Columbia University Medical Center's Department of Psychiatry. "There are a bunch of things that fall into that class," he says. For example, stimulant drugs like Adderall and Dexedrine are nootropics. And even things like caffeine, nicotine, and L-theanine could be considered nootropics, because they have a stimulant effect, he says. "Though, honestly there's nothing that is truly like, Wow, this will make you a genius," he says. Some nootropic supplements claim that they'll make you so smart that you'll have an "unfair advantage," but that is a stretch. For a quick neurology lesson, we know that memory and cognition have to do with various circuits in the brain, Dr. Muskin says. The only way to make your brain work better, so to speak, is to keep using these circuits. "The more we use circuits, the more the synapses grow, and the faster and more efficient [the brain] is," he says. So, taking stimulant drugs or supplements can't make you smarter, but they could make you more focused, which would allow you to get more done, Dr. Muskin says. For example, lots of people assume that taking Adderall makes you better at studying, but it's really just that it helps you concentrate and stay awake or interested. This is also true for any supplement or powder that's marketed as a "nootropic": you can't expect for a powder to make you smarter, but it might energize you a little bit to do your work. There's another place where we give you ALL the goods. Whenever you're buying dietary supplements, it's important to take the claims about fancy-sounding ingredients with a grain of salt. Dietary supplements aren't regulated by the Food and Drug Administration, so products are not subject to the same rigorous testing as medications. "A health food store is there to sell stuff to you," Dr. Muskin says. "Many of these claims are really kind of exaggerated." Not to mention, just picking a random supplement off the shelf of a health food store is not the same thing as going to see a doctor who knows your health history and can make suggestions accordingly. To that same point, you shouldn't take prescription nootropic drugs unless they've been prescribed to you by your doctor or healthcare provider. In this case, "nootropic" is just the latest wellness buzzword for supplement companies to capitalize on to try sell products. If you like consuming nootropic supplements because you believe it "boosts" your brainpower somehow, that's your choice — but not buying into the claims would be the even smarter thing to do.
add to favorites	Free Sample High quality bpc 157 powder	Cars - Economy cars
Free Sample High quality bpc 157 powder BPC 157 powder has a strong anti-inflammatory activity in both acute and chronic inflammation models.In fact, preliminary results in clinical trials suggest that BPC 157 may become an important therapeutic tool for the treatment of inflammatory bowel disease.BPC 157 was shown to accelerate wound healing and to have a marked angiogenic effect.In addition, it significantly facilitates the healing of bone fracture in rats.This peptide also exhibits an osteogenic effect significantly improving the healing of segmental bone defect.BPC 157 accelerates the healing of transected rat Achilles tendon and transected rat quadriceps muscle. FITC-phalloidin staining was able to demonstrate that BPC 157 induces F-actin formation in fibroblasts. Likewise,Western blot analysis was able to detect the production and activation of paxillin and FAK proteins.The western blot analysis also showed that BPC 157 increases the extent of phosphorylation of paxillin and FAK proteins without affecting the amounts produced. Quick Details CAS No.: 137525-51-0 Other Names: bpc-157 peptides MF: C62H98N16O22 EINECS No.: 137525-51-0 Place of Origin: Guangdong, China Type: Auxiliaries and Other Medicinal Chemicals Grade Standard: Medicine Grade Brand Name: Mall Model Number: 137525-51-0 Purity: Min 99% Product Name: BPC 157 Appearance: White Fine Powder CAS: 137525-51-0 Grade: Phamaceutical Grade Assay: HPLC 99% Shelf life: 2 Years Application: White powder Color: White Color Certificate: GMP, HSE, ISO 9001, USP Storage: Cool dried storage
add to favorites	Lab Supply&Better Price Teriparatide Acetate	Cars - Economy cars
Lab Supply&Better Price Teriparatide Acetate CAS 52232-67-4 Teriparatide Acetate powder is a recombinant form of parathyroid hormone consisting of the first (N-terminus) 34 amino acids, which is the bioactive portion of the hormone. It is an effective anabolic(i.e., bone growing) agent used in the treatment of some forms of osteoporosis. It is also occasionally used off-label to speed fracture healing. Teriparatide is identical to a portion of human parathyroid hormone (PTH) and intermittent use activates osteoblasts more than osteoclasts, which leads to an overall increase in bone. Teriparatide is the only anabolic (i.e., bone growing) agent indicated for use in postmenopausal women with osteoporosis at a high risk for fracture or with a history of osteoporotic fracture, patients with multiple risk factors for fracture, and for patients who have failed or are intolerant to other available osteoporosis therapy. It has been FDA-approved since 2002. It is effective in growing bone (e.g., 8% increase in bone density in the spine after one year)[6"> and reducing the risk of fragility fractures. Osteoporosis medications are generally safe, but some side effects of teriparatide include headache, nausea, dizziness, and limb pain.
add to favorites	GMP grade best triptorelin acetate bodybuilding peptide Triptorelin powder	Cars - Economy cars
GMP grade best triptorelin acetate bodybuilding peptide Triptorelin powder Triptorelin Acetate powder, a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-PRO-Gly-NH2), is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts. By causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Like other GnRH agonists, triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction. Triptorelin is marketed under the brand names Decapeptyl (Ipsen) and Diphereline and Gonapeptyl (Ferring Pharmaceuticals). Quick Details CAS No.: 57773-63-4 Other Names: Trifluoroacetate-d5 MF: C66H80F3N18O15 EINECS No.: N/M Place of Origin: Jiangsu, China Type: Auxiliaries and Other Medicinal Chemicals Grade Standard: Medicine Grade Usage: Animal Pharmaceuticals Brand Name: EUBO Model Number: EUBO-PEP18 Purity: 99% Product Name: triptorelin Appearance: White Powder Grade: Phamaceutical Grade CAS: 57773-63-4 Assay: Purity 99% Certificate: ISO Shelf life: 2 Years Function: Health Proctect Package: in vial Sample: Availiable
add to favorites	Best Quality Triptorelin Acetate Peptide Powder 2mg	Cars - Economy cars
Best Quality Triptorelin Acetate Peptide Powder 2mg for Muscle Gain Triptorelin Acetate powder is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using triptorelin at home, a health care provider will teach you how to use it. Be sure you understandhow to use triptorelin. Follow the procedures you are taught when you use a dose. Contact yourhealth care provider if you have any questions.Triptorelin is injected into the muscle.Rotate the injection site. Do not inject into an area of skin that is red, hard, or bruised, or has scarsr stretch marks.Do not use triptorelin if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.Keep this product, as well as syringes and needles, out of the reach of children and away from pets.Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Description : Triptorelin is a releasing hormone agonist used as the acetate or pamoate salts. By causing constant stimulation of the pituitary, it decreases pituitary secretion of luteinizing hormone and follicle stimulating hormone. Like other GnRH agonists, triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, estrogen-dependent conditions, and in assisted reproduction. Triptorelin is marketed under the brand names Decapeptyl and Diphereline and Gonapeptyl. Application : Triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, estrogen-dependent conditions, and in assisted reproduction. Triptorelin is marketed under the brand names Decapeptyl and Diphereline and Gonapeptyl. In the United States, it is sold by Watson as Trelstar.In Iran Triptorelin is marketed under the brand name Variopeptyl.In India, Dr. Reddy's Laboratories has launched recently Triptorelin under the brand name "Pamorelin LA". During the treatment of prostate cancer it does cause a surge, known as a flare effect. In men a reduction of serum levels into the range normally seen after surgical castration occurs approximately two to four weeks after initiation of therapy.
add to favorites	99% Purity Research Grade Peptide Powder Gonadorelin	Cars - Economy cars
99% Purity Research Grade Peptide Powder Gonadorelin Basic Info. CAS:33515-09-2 Sequence:P-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 MF:C55-H75-N17-O13 MW:1182 Purity:99% Specification:2mg/vial, 10mg/vial Appearance:White Lyophilized Powder Standard:USP Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18 C. Upon reconstitution of the peptide it should be stored at 4 C between 2-21 days and for future use below -18 C.Gonadorelin Acetate powder,Gonadorelin powder Description Gonadorelin is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary. In the pituitary GnRH stimulates synthesis and release of FSH and LH, a process that is controlled by the frequency and amplitude of GnRH pulses, as well as the feedback of androgens and estrogens. The pulsatility of GnRH secretion has been seen in all vertebrates, and it is necessary to ensure a correct reproductive function. Thus a single hormone, GnRH, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. Its short half life requires infusion pumps for its clinical use. Gonadorelin USAGE For evaluating the functional capacity and response of the gonadotropes of the anterior pituitary also for evaluating residual gonadotropic function of the pituitary following removal of a pituitary tumor by surgery and/or irradiation. Gonadorelin is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary. In the pituitary GnRH stimulates synthesis and release of FSH and LH, a process that is controlled by the frequency and amplitude of GnRH pulses, as well as the feedback of androgens and estrogens. The pulsatility of GnRH secretion has been seen in all vertebrates, and it is necessary to ensure a correct reproductive function. Thus a single hormone, GnRH, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. Its short half life requires infusion pumps for its clinical use Systemic - Like naturally occurring releasing hormone (GnRH), gonadorelin primarily stimulates the synthesis and release of luteinizing hormone (LH) from the anterior pituitary gland. Follicle-stimulating hormone (FSH) production and release is also increased by gonadorelin, but to a lesser degree. In prepubertal females and some gonadal function disorders, the FSH response may be greater than the LH response. For the treatment of amenorrhea, delayed puberty, and infertility the administration of gonadorelin is used to simulate the physiologic release of GnRH from the hypothalamus in treatment of delayed puberty, treatment of infertility caused by hypogonadotropic hypogonadism, and induction of ovulation in those women with hypothalamic amenorrhea. This results in increased levels of pituitary LH and FSH, which subsequently stimulate the gonads to produce reproductive steroids.
add to favorites	Raw Dianabol Methandienone Powder	Cars - Economy cars
Raw Dianabol Methandienone Powder Dianabol (Dbol) Cycle (methandrostenolone) is made of a different blend of chemicals derived by a Germany-based biochemist group. Methandienone is not the official steroid. It can be sold as an injection or oral drug. It is very potent and is helpful to build muscles. It retains your muscles for a long time. It works the same as Anadrol and Testosterone. Methandienone is the most well known steroid in existance today and was considered to be the ‘breakfast of champions’. It help users produce large gains in muscle mass. Dianabol is often used by body builders and athletes to kick start muscle gains or as a bridge between cycles of other drugs in order to maintain gains. Dbol carries a half-life of 3–5 hours, and many often recommend splitting the daily dose into 2–3 small doses per day in an effort to maintain peak blood levels. However, even with 3 equal doses per day, you will still experience highs and lows in blood levels. Further, the maximum peak blood level will be much lower than it could have been if the total dosing was taken all at once. By taking the total daily dose at once, this will give you a higher peak level that you can time around your training and maximize during the crucial timing window that follows training. Regardless of which method you choose, you will find Dianabol to produce great results. Effects Dianabol is very strong and takes very little time to take effect, by two weeks you will be noticing huge effects from this drug. Some athletes will use it to retain muscle mass while shedding excess fat. With regards to weight gains Dianabol is a champion at making the scales go up and almost nothing can do that faster than this compound. Because of this it is an ideal steroid to take at the start of a steroid cycle, and for this reason it is best used, and almost always used in conjunction with injectable steroids.
add to favorites	Testosterone Cypionate 250mg/Ml, 300mg/Ml Conversion	Cars - Economy cars
Testosterone Cypionate 250mg/Ml, 300mg/Ml Conversion Besides steroid raw materials, some clients always asked us to dissolve steroid powders for them.After dissolving the specific steroid, clients have to filter half-finished product before using it directly when they receive their steroid liquid parcel. The last procedure(filteration) should be done by clients themselves.Test Cyp bodybuilding Test Cypionate 5 gram conversion 20ml @ 250mg/ml Needed 5 grams test cyp 1ml Benzyl Alcohol = 5% BA 15.25 ml sesame oil Syringes 3cc & 5/10cc 18 or 20 gauge needles Mixing Vial Sterile Vial Whatman sterile filter 1. Weigh out 5 grams of powder. 2. Place powder in vial. 3. Add BA to the vial. 4. Heat oil in the oven to help sterilize it, heat to at least 212 degrees F. I usually heat my oil at 275 to be sure, I put the oil in a muffin pan, just fill one of the indentions this is plenty for these experiments. Also heat more oil than you need, as you will not be able to get it all out of the pan. 5. Add oil to the vial, save 2 ml of oil in the syringe for later. Gently shake vial. 6. Heat mixture if necessary. I like heating my powder products, by placing the vial in a frying pan, and placing it on the eye of the stove. 7. Place a 18 or 20 gauge needle in the sterile vial attach whatman sterile filter. 8. Place another needle in the sterile vial to relieve the pressure. 9. Draw out solution with a syringe, run though whatman filter. 10. Take other syringe with 2ml oil, run through whatman into solution. On the other hand, liquid parcel is easier than powder parcel to pass Customs. Anyway, no matter powder parcel or liquid parcel, we all have many effective packing ways correspondingly. So I'm wondering do you have filter equipment? If so, may I know what steroids you want us to dissolve for you, and what concentration you need? For example: My other client want 40 vials of testosterone enanthate 250, ---------------------The concentration is 250mg per ml, 10ml per vial, which means he needs 400ml dissolved liquid, 100g test e. We need to use BA, BB, grapeseed oil and 100g test enan powder to dissolve with our equipment. (As for test enan, we also have other different concentration, it's up to you to choose which kind of dissolved liquid)
add to favorites	Raw Stanozolol Winstrol Winny Powder	Cars - Economy cars
Raw Stanozolol Winstrol Winny Powder Stanozolol (Winstrol) results is a derivative of DHT (dihydrotestosterone) or oxymetholone. It is reported to have a relatively low androgenic effects, but in fact it is much more androgen than oxandrolone. Because of its structure is not capable of aromatases. Claim is that it blocks the production of estrogen by the action of other steroids, with which it is combined. It has been reported its effects are anti-progesteronal, i.e. blocking the formation of progesterone, which is useful for example when combined with nandrolone. Application Winstrol is a kind of lesser substitute for oxandrolone. It raises although modest, but solid and relatively sustained increases in muscle strength accompanied with great increase in strength. Among the athletes, Stanabol use is particularly popular among power athletes, jumpers and sprinters. For bodybuilders, with methenolone, trenbolone or boldenone it is a popular drug for muscle definition. In can be very effective for strength and volume in conjunction with testosterone. Benefits Fast fat burning, even in problem areas; Growth of muscle mass without a set of fluid or fat; The appearance of a relief; The pronounced effect of stiffness and fullness of muscles, especially at the end of the course; Excellent anabolic background; Can be used for bridges between courses; Ideally combined with almost all steroids; Suppresses estrogenic drugs of other drugs; Increases strength and strength endurance; Increases pumping; It is one of the safest steroids; Suitable for both muscle mass and weight loss. Oral VS Injection This is not so with Winstrol, where the oral and injectable preparations are exactly 100% identical to each other. This presents some concerns that the reader must be aware of: The result is a greater amount of hepatotoxicity (liver toxicity), and because both the injectable and oral preparations both possess the hepatotoxic modification of C17-alpha alkylation, they both will place an almost equal level of hepatotoxic strain on the liver. However, the injectable preparation avoids the first-pass through the liver, which allows it to be slightly less hepatotoxic than the oral Winstrol preparation – but hepatotoxic nevertheless, and its duration of use must also have limitations placed on it. Dosage For athletics, physique, and strength, general Winstrol dosages range (with the injectable) around 50 – 100mg administered every other day, equating to around 200 – 400mg per week. In terms of oral Winstrol, this averages to around 60mg per day, and lower dosages of Winstrol (such as 25 – 50mg per day) are said to work well for all groups of users and athletes For females, 5 – 10mg per day of the oral preparation is known to be pretty common among female bodybuilders and athletes that want to avoid any risk of virilization or other side effects, 15mg injected every other day (for an approximate total of 60mg per week) is a good recommendation.
add to favorites	Stanozolol Powder China,Oxymetholone Manufacturer	Cars - Economy cars
Stanozolol Powder China,Oxymetholone Manufacturer (Toledo News Now) The City of Perrysburg remains under a do not drink advisory. Unless Oxymetholone Manufacturer the City of Perrysburg receives information from the City of Toledo contrary to this position, we will be opening the Perrysburg water filling station at Perrysburg Stanozolol Powder High School Baseball Fields on Fort Meigs Road in . Please remember to bring your own containers to the filling station.We will provide updates to the residents as this information becomes available from the City of Toledo. Please stay Buy Viagra Uk Tesco tuned to local media outlets this evening in the event that new information becomes available.Stanozolol (Winstrol) dosage The City of Rossford is distributing gallon sized water bottles to Wood County residents today from 2:00 pm to 6:00 pm at the Rossford High School Bulldog Center located at 719 Superior St. (SR 65). The tap water is still contaminated and should not be consumed. An update from the Wood County EMA did not include any information as to Methandienone China when tap water will be safe for consumption. Water is available, for free, to Rossford residents who are shut ins or elderly and this water will be delivered by Rossford Firefighters to your home by calling 419 666 0210, Extension 230. Leave your name address and telephone number if you get voicemail. Please inform your handicapped or elderly neighbors of this service and check on them regularly. Some options available at this time include:Northwestern Water Sewer District Headquarters12560 Middleton Pike (State Route Cheap Kamagra London 582)Bowling Green, Ohio 43402A Buy Kamagra Uk watershed is available in the parking lot for you to fill your own containers. This site issupplied by the City of Bowling Green public water system.Northwestern Water Sewer DistrictStoney Ridge Watershed5501 Fremont PikeStoney Ridge, OhioThis site is supplied by a water well so the water is safe but does not produce a lot of water.Northwestern Water Sewer DistrictBowling Green Watershed990 Haskins RoadBowling Green, OhioThis watershed site is supplied by Buy Kamagra Uk Next Day the City of Bowling Green public water system.There is a limited amount of bottled water available for Buy Kamagra Next Day Delivery distribution as supplies becomeavailable. You must be a Wood County resident and you will be given one case of water asCity of Perrysburg Distribution Point (starting on Sunday if needed)
add to favorites	Sustanon-250-Liquid-Conversion-Bb-Ba-	Cars - Economy cars
Sustanon-250-Liquid-Conversion-Bb-Ba- Besides steroid raw materials, some clients always asked us to dissolve steroid powders for them.Sustanon 250 dosage After dissolving the specific steroid, clients have to filter half-finished product before using it directly when they receive their steroid liquid parcel. The last procedure(filteration) should be done by clients themselves. )Sustanon 250ml @ 400mg/ml Grapeseed oil: 168ml Benzyl Alcohol: 15ml On the other hand, liquid parcel is easier than powder parcel to pass Customs. Anyway, no matter powder parcel or liquid parcel, we all have many effective packing ways correspondingly. So I'm wondering do you have filter equipment? If so, may I know what steroids you want us to dissolve for you, and what concentration you need? For example: My other client want 40 vials of testosterone enanthate 250, ---------------------The concentration is 250mg per ml, 10ml per vial, which means he needs 400ml dissolved liquid, 100g test e. We need to use BA, BB, grapeseed oil and 100g test enan powder to dissolve with our equipment. (As for test enan, we also have other different concentration, it's up to you to choose which kind of dissolved liquid) Our prices of steroid powders and steroid half-finished products are based on clients' detailed order. Sustanon cycles are almost always wet bulking cycles. In fact, I don't think I've seen guys trying to get lean with sustanon as a base .Sustanon 250 Beginner/Intermediate Bulking Cycle
add to favorites	Type 2 Diabetes Drug Liraglutide powder	Cars - Economy cars
Type 2 Diabetes Drug Liraglutide powder Victoza falls under the umbrella of incretin mimetics, a class of drugs used to treat type 2 diabetes that works by boosting insulin production in the pancreas, lowering the patient’s blood sugar levels.Liraglutide powder Victoza, which is manufactured by Novo Nordisk, was first approved for market in 2010. It quickly became one of the most popular type-2 diabetes treatments. However, more recently Victoza has faced criticisms over its dangerous side effects, which Novo Nordisk failed to warn consumers about. As a result, a number of Victoza lawsuits have been filed against the manufacturer on behalf of individuals who were injured by Victoza.Byetta (exenatide) is a GLP-1 receptor agonist which mimics the effect of glucagon-like peptide-1, a hormone that increases insulin production when blood sugar is high. Byetta is administered as a twice-daily injection. Bydureon is also a GLP-1 receptor agonists and contains the same main ingredient as Byetta – exenatide. Bydureon is a longer-lasting version of Byetta, requiring a once a week injection. Rather than an injection, Januvia (sitagliptin) is a once-daily pill used to lower blood glucose levels in patients with Type 2 diabetes. Januvia helps to increase the insulin produced by the pancreas when blood sugar levels are high and help to reduce the amount of sugar produced by the liver. Also a pill, Janumet is a combination drug – it combines sitagliptin and metformin into a single pill. Researchers have linked Victoza to a number of dangerous and potentially life-threatening side effects. These side effects were not included on the original Victoza warning label and the public has now been made aware of these side effects by researchers and through drug safety communications. Pancreatitis and Pancreatic Cancer — Following a number of concerning reports linking Victoza to pancreatitis, the U.S. Food and Drug Administration (FDA) conducted an investigation into Victoza health risks in 2013. The FDA found that pancreatitis was more likely to occur in patients using Victoza than in patients using any other type-2 diabetes medication. As a result, the FDA mandated a black box warning making consumers aware of Victoza’s increased risk of pancreatitis. Other research and studies have shown that this form of type-2 diabetic treatment may be linked to pancreatic cancer. In a recent clinical trial, 13 patients were diagnosed with pancreatic cancer while only 5 patients taking the placebo were diagnosed with pancreatic cancer. Thyroid Cancer — Following a number of concerning reports linking Victoza to thyroid cancer, the U.S. Food and Drug Administration (FDA) mandated a black box warning for the drug, the strongest warning a drug can carry. Researchers found an increased risk of tumors — sometimes cancerous — developing in the thyroid glands of rats and mice. If you are taking Victoza and have developed pancreatic cancer, pancreatitis, or thyroid cancer, you should stop taking Victoza and talk to your doctor and an experienced personal injury lawyer right away. If you had previously taken Victoza and have developed pancreatic cancer, pancreatitis, or thyroid cancer, you should contact an experienced personal injury lawyer right away.
add to favorites	FDA approves Novo Nordisk’s type 2 diabetes drug Liraglutide powder	Cars - Economy cars
FDA approves Novo Nordisk’s type 2 diabetes drug Liraglutide powder Novo Nordisk has secured approval for Liraglutide powder (liraglutide) from the US Food and Drug Administration (FDA) to treat paediatric patients aged ten years or older with type 2 diabetes. Victoza is claimed to be the first non-insulin drug approved to treat the condition in paediatric patients. It has been used for adult patients since 2010. Acting director at the FDA Center for Drug Evaluation and Research’s Division of Metabolism and Endocrinology Products (DMEP) Lisa Yanoff said: “Victoza has now been shown to improve blood sugar control in paediatric patients with type 2 diabetes. “The expanded indication provides an additional treatment option at a time when an increasing number of children are being diagnosed with this disease.”When administered, Victoza works by creating the same effects in the body as the glucagon-like peptide (GLP-1) receptor protein in the pancreas and improves blood sugar levels. Victoza slows digestion, prevents the liver from making too much glucose, and helps the pancreas produce more insulin when needed. It can also be used to reduce the risk of major adverse cardiovascular (CV) events in adults with type 2 diabetes and established CV disease. Novo Nordisk carried out several placebo-controlled trials in adults and one placebo-controlled trial with 134 pediatric patients to evaluate the efficacy and safety of Victoza for reducing blood sugar in patients with type 2 diabetes. The drug is not a substitute for insulin and is not indicated for patients with type 1 diabetes or those with diabetic ketoacidosis. No clinical trials were conducted to study the effect of the drug on major adverse CV events in paediatrics.
add to favorites	Semaglutide aids T2DM weight loss over 2 years	Cars - Economy cars
Semaglutide aids T2DM weight loss over 2 years LISBON – The investigational glucagon-like peptide (GLP)-1 receptor agonist semaglutide added to standard care for type 2 diabetes mellitus (T2DM) resulted in clinically significant weight loss over 2 years in the SUSTAIN-6 phase 3 trial. Participants treated with semaglutide in the study lost an average of 3.6 to 4.9 kg, depending on the dose they were given (0.5 mg or 1.0 mg), which was significantly (P less than .0001) more than those who were randomized to matching placebos (-0.7 mg and -0.5 mg).“A dose-response effect was observed on weight loss with semaglutide treatment,” study investigator Agostino Consoli, MD, reported at the annual meeting of the European Association for the Study of Diabetes. Semaglutide is under development by Novo Nordisk and is currently under review by regulatory agencies in the United States, Europe, and Japan. It has 94% homology to human GLP-1 and modifications have been made to help it avoid degradation and which give it a half-life that allows it to be given once a week. SUSTAIN 6 is part of an ongoing phase 3 program and is a long-term outcome study with the primary objective of evaluating the cardiovascular safety of semaglutide. Effects on macro- and microvascular complications, glycemic control, body weight, body mass index and weight circumference are key secondary endpoints, together with assessment of its overall safety and tolerability.GHRP-2 powder,GHRP 2 powder Other trials in the program, have evaluated treatment with semaglutide as monotherapy (SUSTAIN 1; Lancet Diabetes Endocrinol. 2017;5:251-60) or versus other treatments including sitagliptin (Januvia, Merck; SUSTAIN 2; Lancet Diabetes Endocrinol. 2017;5:341-54), exenatide extended release (Bydureon, AstraZeneca; SUSTAIN 3), or insulin glargine (SUSTAIN 4), as add-on to basal insulin with or without metformin (SUSTAIN 5), and most recently, versus dulaglutide (Trulicity, Eli Lilly; SUSTAIN 7). SUSTAIN 6 involved 3,297 people with T2DM with established cardiovascular disease or chronic kidney disease or otherwise identified as being at increased cardiovascular risk, according to Dr. Consoli, who is an endocrinologist and professor at the University of Chieti-Pescara, Italy. The results of the primary endpoint have been reported (N Engl J Med. 2016; 375:1834-44) and showed that the composite rate of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke was significantly lower among patients receiving semaglutide than among those receiving placebo. The hazard ratio for the reduction in the composite endpoint was 0.74 (95% CI, 0.58-.95; P less than .001 for noninferiority). Results of the secondary analyses reported by Dr. Consoli at EASD 2017 showed that semaglutide could help more patients than placebo achieve significant weight loss, which could help further reduce their cardiovascular risk. He reported that a 5% or greater weight loss at 2 years was achieved by 36% and 47% of patients treated with semaglutide 0.5 mg and 1 mg groups, respectively, and by 18% and 19% of patients in the matching placebo groups (P less than .0001 for both comparisons). A 10% or greater weight loss was achieved by 13% and 21% of the semaglutide-treated patients and by 6% and 7% of those given placebo. “The effect of weight was not dependent on BMI [body mass index] at baseline,” Dr. Consoli said, emphasizing that there was a consistent reduction in the weight in all BMI categories. Importantly, Dr. Consoli observed, the effects of semaglutide on weight seen were not driven by just a few patients losing weight, and around 80% of patients in the study experienced some degree of weight loss. “As expected, the subjects treated with the GLP-1a had more GI [gastrointestinal] effects,” Dr. Consoli reported. Nausea or vomiting were reported in twice as many patients treated with semaglutide 0.5 mg (21.9%) and 1 mg (27.3%) as their placebo-matched counterparts (10.8% and 10.6%). A post-hoc analysis found that the effect of semaglutide on weight loss was not likely to be down to these side effects, however, with a similar weight reductions seen in those who did and did not experience nausea or vomiting. The “estimated natural direct effect of treatment” was -2.75 kg for the 0.5 mg dose and -4.32 for the 1 mg dose of semaglutide versus their placebos Dr. Consoli said. GI drove the weigjht loss to a small degree; -0.12 kg and -0.04 kg of weight loss seen in the 0.5 mg and 1 mg semaglutide groups versus their placebos could be ascribed to nausea or vomiting. In a poster presentation at the meeting, data on another post-hoc analysis from the SUSTAIN phase 3 program were reported. In a responder analysis of T2DM patients achieving glycemic and weight loss thresholds, a greater proportion of those treated with semaglutide achieved clinically meaningful reductions in both glycated hemoglobin (HbA1c) and body weight than those given comparator treatments. The composite endpoint of at least a 1% reduction in HbA1c and a 5% or greater decrease in body weight was achieved by 25%–35% of patients treated with the 0.5 mg dose of semaglutide, by 38%–56% of those given the higher dose, and by 2%–13% or all comparators (P less than .0001). The higher dose of semaglutide also allowed more people to achieve this endpoint than the lower dose. Novo Nordisk supported the study. Dr. Consoli disclosed receiving research funding from AstraZeneca and Novo Nordisk and speaker’s bureau or consultation fees from AstraZeneca, Boehringer Ingelheim, Eli Lilly & Co., Merck, Sharp & Dohme, Novartis, Sanofi-Aventis, and Takeda.
add to favorites	Tesamorelin (Egrifta) comes on – what you need to know	Cars - Economy cars
Tesamorelin (Egrifta) comes on – what you need to know Last week, Theratechnologies Inc. began marketing a new medicine called tesamorelin (Egrifta)—licensed for the treatment of excess belly fat in some HIV-positive people. Tesamorelin powder causes the body to produce growth hormone and, as a result, most tesamorelin users can lose some degree of belly fat. Summary Tesamorelin is a small molecule that stimulates the brain to produce growth hormone. This hormone helps to reduce the amount of fat in the belly of some HIV-positive people. Tesamorelin does not affect the fatty layer just under the skin (subcutaneous fat) in the face or other parts of the body. Prior to prescribing tesamorelin, Health Canada requires physicians to request a CT scan of a patient’s abdomen to confirm the presence of excess belly fat. Tesamorelin is injected under the skin once daily. In clinical trials, participants who had previously lost belly fat while taking tesamorelin had belly fat return when they stopped taking the drug. In Canada, tesamorelin is expected to cost about $3,000 per patient per month. Some notes on belly fat, growth hormone and HIV The fat that accumulates within the belly is called visceral fat. In general, among adults, as the amount of belly fat increases, production of growth hormone decreases. Studies from the 1980s and early-to-mid-1990s suggested that some HIV-positive adults produced lower-than-ideal levels of growth hormone. This reduced production of growth hormone led to changes in the composition of the body—an accumulation of belly fat and a loss of some lean tissue (muscle). About tesamorelin Tesamorelin is a small molecule (called a peptide). This drug stimulates a gland in the brain, called the pituitary gland, to release growth hormone. Increased production of growth hormone can cause excess belly fat to diminish. Clinical trials with HIV-positive people Tesamorelin has been tested in more than 800 HIV-positive people in well-designed clinical trials. Many participants used tesamorelin for between six and 12 months. This usually resulted in a significant decrease in belly fat compared to placebo (fake tesamorelin). There was a small increase in muscle mass among tesamorelin users and no loss of subcutaneous fat. Levels of triglycerides, a fatty substance in the blood, decreased modestly among tesamorelin users. When participants who had previously received tesamorelin were instead given placebo, all of the beneficial effects of tesamorelin disappeared. The hormone insulin is used to help regulate blood sugar levels. After initiating therapy with tesamorelin, the body’s ability to respond to insulin may change. During clinical trials, participants who received tesamorelin were more likely to develop elevated levels of blood sugar because their bodies became less sensitive to the effects of insulin. However, among participants who took tesamorelin for up to one year, problems with blood sugar levels generally resolved.
add to favorites	Gonadorelin Market Research	Cars - Economy cars
Gonadorelin Market Research, Key Vendors, Opportunity, Size, Trends Analysis And Regional Forecast To 2026 Verified Market Research represents the Gonadorelin Market 2026. Detail analysis of the parent market based on Key players, present, past and artistic movement information which is able to offer as a profitable guide for all Gonadorelin Market competitors. The analysis Advanced Gonadorelin Market covers an overview of the industry policies that Gonadorelin Market considerably, the price structure of the product obtainable in the market, and their producing chain. Gonadorelin business report is helpful for future strategy development, and to know about Market Drivers, Restraints, Opportunities, and Global Market Size, Share, Growth, Trends, Key players forecast to 2026.Gonadorelin Acetate powder,Gonadorelin powder The study provides detailed information on the established Gonadorelin Market with a strong perceptive of world market players and emerging market associations through market research reports. This also includes producing Analysis, Size, Share, Supply, Demand, CAGR, Forecast Trends, Sales, Production, and Business Trends. The report covers a detailed analysis of growth factors, constraints, opportunities, and challenges Gonadorelin Market. It additionally includes extensive analysis on the latest trends in the market to determine Gonadorelin Market growth. The report aims to produce an overview of world Gonadorelin market with careful market segmentation. Also, it analyses this Gonadorelin market situation and forecasts the market until 2026. The report covers market dynamics affecting the market throughout the forecast period. What is more, the report analyses the competitive scenario, geographic trends, and opportunities within the markets with regard to all geographic regions. The report conjointly includes the elaborated company profiles of the key players within the market beside their market methods.
add to favorites	FOR USE IN SYNCHRONIZATION PROGRAMS WITH LUTALYSE®	Cars - Economy cars
FOR USE IN SYNCHRONIZATION PROGRAMS WITH LUTALYSE® Delays in rebreeding can be costly. Synchronization programs with producer- and veterinarian-trusted products from Zoetis result in more efficient breeding, saving time and protecting your bottom line. FACTREL® Injection (gonadorelin injection) has an FDA-approved label to be used in conjunction with LUTALYSE® Injection (dinoprost injection) to synchronize estrous cycles to allow for fixed-time artificial insemination (FTAI) in lactating dairy cattle.Gonadorelin Acetate powder,Gonadorelin powder FACTREL is now available in a larger, more convenient 50-mL bottle. Now you can treat up to 25 cows per bottle of FACTREL compared with just 10 doses in the 20-mL bottle. With more than 12,000 total cows studied, you can have confidence that FACTREL is effective. Now you can adapt a reproduction program that fits your management needs, with flexible schedule and dosing with FACTREL and LUTALYSE. FACTREL is also indicated for the treatment of ovarian follicular cysts in cattle. When used in cattle with ovarian follicular cysts, treatment effect is to reduce the number of days to next estrus. It’s more than just the bottle. Zoetis works with you to make appropriate decisions about the use of LUTALYSE and FACTREL in your herds and to create a comprehensive approach for your reproduction program, so you can set and achieve higher pregnancy rate goals, improving your milk production and increasing the opportunities you have for herd improvement through genetic selection.
add to favorites	How to use cjc-1295 and ghrp-6 reconstitution	Cars - Economy cars
How to use cjc-1295 and ghrp-6 reconstitution When ready to reconstitute remove your vial from the fridge and pop the top cap; Kept within a fridge most will find 4 to 6 weeks without significant 1 mcg/kg is considered ones situation dose; in reference the GHRP-6 powder,GHRP 6 powder and GHRH usage. of Female Use of the Synthetic Growth Hormone CJC Pulses. In addition when using GHRP-6 for GH release, the average dosing GRF ( sometimes still referred to by its old name as “CJC without DAC”). When the powdered form of your peptide is reconstituted, it will then. What are your thoughts on the best ways to reconstitute these two peptides. I have seen various protocols posted. My CJC is 2mg and GHRP-6 is 5mg. That's why you use 2x GHRP vs cjc or at least thats the way I. It seems contrary to what I've heard before about CJC only being injected once a **TL;DR: Dosage schedule for GHRP6 + CJC?. Say they has 2mg of cjc and 5mg of ghrp in vials; any thing special that 5mgs of ghrp-6) and what will the resulting dosage/concentration be. Will Mod CJC and GHRP6 last longer in NaCL or BW? I know it can be recon in BW for approximately 2 weeks, but what if you want it to. This seems to be the most effective dosing schedule. This cycle has done the best for most people running CJC + GHRP-6 You can substitute GHRP-2 for. GHRP-6 doses can vary depending on goals and past experience. with doses of a GHRH analogue, such as Mod GRF (CJC without . For reconstitution, users will typically mix 3ml of bacteriostatic water with the powder gently. How to Mix and Store Peptides for its types GHRP Peptides, CJC Peptides, HGH Frag and IGF-1 Peptides. a. to aim at the wall instead of directly at the powder for better dilution and mixing of substances. e. Cjc ghrp 2 dosage instructions >> [ Read Online ] wise to use GHRP along with CJC if you want toThe GHRP 6 can also be used. The only GHRH to consider is tetra-substituted CJC / CJC(without DAC) / modGRF(). They are all GHRP-6 is very potent and makes you quite hungry. GHRP-2 GH pulses should peak within about 10 minutes after dosage. Nice post, the CJC GHRH analog is a very quality substance. CJC or GRF () – the best choice for the combination. Enhance the effect of GHRP-6 in several times. This combination is currently. Blend CJC NO DAC with GHRP-6 is Stable at room Temperature. Blend CJC NO DAC with GHRP-6 should be refrigerated at temperatures not to. The principal use of CJC is to provide CJC is typically provided in vials . GHRP-6 – 5mg Other Peptides; Peptides; Reconstituting Agents; Research. For short term (per vial use)it's refrigerate I know but long term? The reconstitution agent for both CJC & GHRP-6 is Bacteriostatic Water. After reconstituting CJC W/O DAC should be refrigerated at temperatures Generally, a product in the GHRH category, including CJC, is chosen as an alternate to using GH, and only rarely GHRP-6 10mg/vial 10vials/kit 1g/bag. Research Calculator to Reconstitute Proteins & Peptides. This tool determines peptide weight in micrograms (mcg) in each graduated unit of a container or. Muscle Building Growth Hormone Releasing Peptide 5mg/vial GHRP-6 guidelines for reconstituting GHRP-6, reconstitute in sterile, bacteriostatic, distilled water, Synonyms: CJC without DAC, CJC w/o DAC, MOD GRF , Neorelin, The most common use of these peptides is to increase GH production.