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Category Cars
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Created 2019-10-30
Owner freemexy
Title Tadalafil Powder Steroids Tadalafil Powder
Description Tadalafil Powder Steroids Tadalafil Powder Tadalafil is a PDE5 inhibitor marketed in pill form for treating erectile dysfunction (ED) under the name Tadalafil, and under the name Adcirca for the treatment of pulmonary arterial hypertension. Tadalafil powder dosage Tadalafil's pharmacologic distinction is its longer half-life (17.50 hours) resulting in longer duration of action, and so partly responsible for "The Weekend Pill" sobriquet. Furthermore, the longer half-life is the basis for current investigation of tadalafil's daily therapeutic use in relieving pulmonary arterial hypertension. Daily tadalafil has the potential to be a treatment option for Peyronie’s disease (PD), according to data presented at the Sexual Medicine Society of North America 18th Annual Fall Scientific Meeting in San Antonio, Texas. In a small study of PD patients, treatment with the drug, a phosphodiesterase type 5 (PDE5) inhibitor that is FDA approved for treating erectile dysfunction, was associated with decreased pain on erection and degree of penile curvature and improved erectile function. Hyun Jun Park, MD, PhD, and Nam Cheol Park, MD, PhD, from Pusan National University School of Medicine in Busan, Korea, divided 66 PD patients into 3 groups: Group 1, which included 20 patients treated with an intralesional injection of verapamil (IVI); group 2, which included 23 patients treated with tadalafil 5 mg once daily for 12 weeks; and group 3, which included 23 patients who received IVI and tadalafil 5 mg once daily for 12 weeks. Groups 1, 2, and 3 had means ages of 53.2, 56.1, and 55.3 years, respectively. At baseline, the groups had no significant differences in age, erectile function, or duration and characteristics of PD, according to the researchers. Pain resolution was achieved in 55%, 70%, and 78.3% of groups 1, 2, and 3, respectively, after 12 weeks, the researchers reported in a poster presentation. The changes in the mean degree of penile curvature were -4.6, -6.2, and -7.2 degrees, respectively. The changes in mean plaque size were 0.2, 0.2, and 0.3 cm2. Further, groups 2 and 3 showed a greater increase in International Index of Erectile Function (IIEF)-Erectile Function domain score compared with group 1 (3.8 and 3.8 vs 0.4, respectively). Commonly reported adverse events (AEs) included hematoma at the injection site (4 cases), myalgia (3 cases), and dyspepsia, headache, and flushing (1 case each). No patient discontinued treatment due to AEs, the investigators reported.
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